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In the early 2000s, eight cases of bronchiolitis obliterans were reported to Missouri health authorities, with all sufferers reporting former employment at the same microwave popcorn plant

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This pivot is supported by varying levels of public health endorsement for the reduced-risk product category

These postmarketing reports have included changes in mood (including depression and mania), psychosis, hallucinations, paranoia, delusions, homicidal ideation, aggression, hostility, agitation, anxiety, and panic, as well as suicidal ideation, suicide attempt, and completed suicide